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<b>Can accutane make you infertile?</b> Long-term effect of systemic isotretinoin on female fertility. Systemic isotretinoin is the only drug which acts on all of the etiopathogenic mechanisms of acne. Isotretinoin has some well-known side effects. Besides these, there is a suspicion whether it affects fertility or not.
<b>Can Accutane cause birth defects years later?</b> Accutane, also known as isotretinoin, is known to cause birth defects, including brain, heart, and face deformities, if women take it while pregnant. Because of this, it is recommended that women of childbearing age taking the drug be tested for pregnancy before starting it and then repeatedly during their treatment.
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